|Joseph Barakat |
B.S., Chemical Engineering,
Columbia University, 2012
M.S., Chemical Engineering,
Stanford University, 2014
Email: jbarakat @ stanford . edu
Dynamics of Flexible Particles Under Confinement
"Soft particles" are microscopic objects that deform under modest stresses. Such materials are ubiquitous in multiphase flows, with examples ranging from industrial processes (e.g. emulsion drops and polymer gels) to biological systems (e.g. vesicles and red blood cells). The transport of soft particles through flow channels is significantly altered when the particle size is on the order of the channel hydraulic diameter, giving rise to a rich assortment of hydrodynamic phenomena that can be broadly classified as "confinement effects." Applications relevant to these phenomena include the transport of encapsulants for drug delivery, passage of red-blood cells through microcapillaries, and high-throughput sequencing in microfluidic devices.
My research centers on investigating single- and multi-particle dynamics in confined flows using a combination of analytical theory and numerical simulation. Currently, I am interested in 1) how the material properties of a flexible particle - be it a fluid sac or contiguous gel - affects mobility under confinement; and 2) the collective behavior of trains of particles in fully confined geometries.
Fig 1: Simulations of elastic capsules in channel flow. (Left) Initial condition for the simulation is a linear array of capsules in a periodic unit cell. (Right) Plot of center-of-mass positions relative to the first capsule as a function of time.